Searchable abstracts of presentations at key conferences in endocrinology

ea0003p278 | Thyroid | BES2002

The female preponderance to autoimmune thyroid disease is reduced in multiplex type 1 diabetes families

Tait K , Berman J , Carr-Smith J , Rowe B , Heward J , Franklyn J , Todd J , Bain S , Barnett A , Gough S

Autoimmune thyroid diseases (AITD), such as Graves' disease (GD) and autoimmune thyroiditis (AT), cluster within families and within individuals and exhibit a strong female preponderance. The type 1 diabetes Warren Repository was established between 1989 and 1996 and contains 505 families of British white Caucasian origin. Each family consists of both parents and at least two siblings with type 1 diabetes. We have examined the clinical data collected to establish the frequency...